Anti-Human KDM3A Polyclonal Antibody (HP526014)

Name: Anti-Human KDM3A Polyclonal Antibody
Brand: abinScience
SKU: HP526014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HP526014

Description

Anti-Human KDM3A Polyclonal Antibody (HP526014) is a rabbit polyclonal antibody detecting KDM3A in ELISA, IHC, WB. Suitable for Mouse, Chicken, Human, Rat, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KDM3A (Thr941-Pro1321).

Target

KIAA0742, KDM3A, JMJD1, Jumonji domain-containing protein 1A, Lysine-specific demethylase 3A, [histone H3]-dimethyl-L-lysine(9) demethylase 3A, JmjC domain-containing histone demethylation protein 2A, TSGA, JHDM2A, JMJD1A

Purification

Purified by antigen affinity column.

Accession

Q9Y4C1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Lysine-specific demethylase 3A (KDM3A) is a ~147 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin.

Note

For research use only.

Images

References

Datasheet

Anti-Human KDM3A Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human KDM3A Polyclonal Antibody (HP526014)

Overview

Images

References

Datasheet

SDS

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