Anti-Human KDM4A IP Recombinant Antibody (SAA0204) (HF843013)

Name: Anti-Human KDM4A IP Recombinant Antibody (SAA0204)
Brand: abinScience
SKU: HF843013
Price: 191 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF843013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA0204

Clonality

Monoclonal

Target

Lysine-specific demethylase 4A, JMJD2, Jumonji domain-containing protein 2A, KDM4A, KIAA0677, JHDM3A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, JMJD2A, JmjC domain-containing histone demethylation protein 3A

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75164

RRID

Anti-Human KDM4A IP Antibody (SAA0204) (abinScience Cat# HF843013, RRID:AB_3729738)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Lysine-specific demethylase 4A (KDM4A/JMJD2A) is a ~120 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Also able to demethylate histone H1-4 methylated at 'Lys-26' (H1.4K26me1, H1.4K26me2 and H1.4K26me3).

1. Whetstine, JR. et al. (2006) Cell 125, 467-81. PMID: 16603238

2. Bavetsias, V. et al. (2016) Journal of medicinal chemistry 59, 1388-409. PMID: 26741168

3. Tan, MK. et al. (2011) Molecular and cellular biology 31, 3687-99. PMID: 21768309

4. Trojer, P. et al. (2009) The Journal of biological chemistry 284, 8395-405. PMID: 19144645

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human KDM4A IP Antibody (SAA0204)

References

Datasheet

Anti-Human KDM4A IP Recombinant Antibody (SAA0204).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human KDM4A IP Recombinant Antibody (SAA0204) (HF843013)

Overview

Images

References

Datasheet

SDS

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