

| Catalog No. | HP904014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KDM4D Polyclonal Antibody (HP904014) is a rabbit polyclonal antibody detecting KDM4D in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human KDM4D (Asn17-Ala354). | ||||||||
| Target | Lysine-specific demethylase 4D, JHDM3D, [histone H3]-trimethyl-L-lysine(9) demethylase 4D, KDM4D, JmjC domain-containing histone demethylation protein 3D, JMJD2D, Jumonji domain-containing protein 2D | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q6B0I6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Lysine-specific demethylase 4D (KDM4D) is a ~58 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. | ||||||||
| Note | For research use only. |
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