

| Catalog No. | HA269014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KDM5D Polyclonal Antibody (HA269014) is a rabbit polyclonal antibody detecting KDM5D in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human KDM5D (Gly374-Asp611). | ||||||||
| Target | Jumonji/ARID domain-containing protein 1D, [histone H3]-trimethyl-L-lysine(4) demethylase 5D, H-Y, JARID1D, HY, SMCY, KDM5D, Histone demethylase JARID1D, HYA, Lysine-specific demethylase 5D, KIAA0234, Histocompatibility Y antigen, Protein SmcY | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9BY66 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Lysine-specific demethylase 5D (KDM5D) is a ~174 kDa protein. Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. | ||||||||
| Note | For research use only. |
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