

| Catalog No. | HT034014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human KIF5C (Met1-Thr330). | ||||||||
| Target | Kinesin heavy chain isoform 5C, KIAA0531, KIF5C, Kinesin heavy chain neuron-specific 2, NKHC2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O60282 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Kinesin heavy chain isoform 5C (KIF5C) is a ~109 kDa protein. Microtubule-associated force-producing protein that may play a role in organelle transport. Has ATPase activity. Involved in synaptic transmission. Mediates dendritic trafficking of mRNAs. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. 1. Willemsen, MH. et al. (2014) Journal of medical genetics 51, 487-94. PMID: 24812067 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-KIF5C polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat cerebellum lysate
Lane 3: Rat brain lysate
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