

| Catalog No. | HC085014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KLF10 Polyclonal Antibody (HC085014) is a rabbit polyclonal antibody detecting KLF10. Suitable for Human, Mouse, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human KLF10 (Lys382-Gln480). | ||||||||
| Target | EGR-alpha, KLF10, Krueppel-like factor 10, TGFB-inducible early growth response protein 1, TIEG, TIEG-1, TIEG1, Transforming growth factor-beta-inducible early growth response protein 1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q13118 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Krueppel-like factor 10 (KLF10) is a ~52 kDa protein. Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation. | ||||||||
| Note | For research use only |
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