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Anti-Human KLF7 Polyclonal Antibody (HF692014)

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Overview
Catalog No.HF692014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human KLF7 (Met1-Ser175).
Target Krueppel-like factor 7, UKLF, KLF7, Ubiquitous krueppel-like factor
Purification Purified by antigen affinity column.
Accession O75840
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Krueppel-like factor 7 (KLF7) is a ~33 kDa protein. Transcriptional factor. Plays a critical role in neuronal morphogenesis and survival of sensory neurons. Represses the corneal epithelium differentiation. Also acts as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells. Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin.

1. Kawamura, Y. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 844-56. PMID: 16339272
2. Matsumoto, N. et al. (1998) The Journal of biological chemistry 273, 28229-37. PMID: 9774444
3. Klein, RH. et al. (2017) The Journal of biological chemistry 292, 18937-18950. PMID: 28916725
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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