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Anti-Human KRT8/18 Recombinant Antibody (SAA1385) (HY427023)

Anti-Human KRT8/18 Recombinant Antibody (SAA1385)
Anti-Human KRT8/18 Recombinant Antibody (SAA1385)
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Overview
Catalog No.HY427023
Species reactivityHuman
ApplicationsELISA, FuncS, IHC
Host speciesMouse
IsotypeIgG1, kappa
Clone IDSAA1385
Clonality Monoclonal
Target Type-II keratin Kb8, CYK8, Keratin-8, KRT8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, K8, Cytokeratin-18, CYK18, K18, Keratin, type I cytoskeletal 18, KRT18, CK-18, Keratin-18, Cell proliferation-inducing gene 46 protein
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P05787, P05783
RRID

Anti-Human KRT8/18 Antibody (SAA1385) (abinScience Cat# HY427023, RRID:AB_3726902)
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Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Keratin, type II cytoskeletal 8 (KRT8/KRT18) is a ~53 kDa protein. Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

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1. Fujiwara, S. et al. (2016) Molecular biology of the cell 27, 954-66. PMID: 26823019
Note For research use only.
Images
  • Anti-Human KRT8/18 Recombinant Antibody (SAA1385)

    SDS-PAGE

    SDS-PAGE for Anti-Human KRT8/18 Antibody (SAA1385).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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