Anti-Human LDLR Polyclonal Antibody (HF521024)

Name: Anti-Human LDLR Polyclonal Antibody
Brand: abinScience
SKU: HF521024
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF521024

Description

Anti-Human LDLR Polyclonal Antibody (HF521024) is a rabbit polyclonal antibody detecting LDLR. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LDLR (Asp415-Leu568).

Target

LDL receptor, LDLR, Low-density lipoprotein receptor

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P01130

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Low-density lipoprotein receptor (LDLR) is a ~95 kDa protein. Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization.

1. Riad, A. et al. (2018) Scientific reports 8, 16845. PMID: 30443021

Note

For research use only

Images

References

Datasheet