Anti-Human LETM1 Polyclonal Antibody (HF870014)

Name: Anti-Human LETM1 Polyclonal Antibody
Brand: abinScience
SKU: HF870014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HF870014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LETM1 (Leu231-Thr426).

Target

LETM1, Leucine zipper-EF-hand-containing transmembrane protein 1, Mitochondrial proton/calcium exchanger protein

Purification

Purified by antigen affinity column.

Accession

O95202

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Mitochondrial proton/calcium exchanger protein (LETM1) is a ~83 kDa protein. Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.

1. Tamai, S. et al. (2008) Journal of cell science 121, 2588-600. PMID: 18628306

2. Jiang, D. et al. (2009) Science (New York, N.Y.) 326, 144-7. PMID: 19797662

3. Tsai, MF. et al. (2014) The Journal of general physiology 143, 67-73. PMID: 24344246

4. De Marchi, U. et al. (2014) The Journal of biological chemistry 289, 20377-85. PMID: 24898248

5. Huang, E. et al. (2017) Nature communications 8, 1399. PMID: 29123128

6. Nakamura, S. et al. (2020) Communications biology 3, 99. PMID: 32139798

7. Kaiyrzhanov, R. et al. (2022) American journal of human genetics 109, 1692-1712. PMID: 36055214

8. Austin, S. et al. (2022) EMBO reports 23, e54978. PMID: 36321428

Note

For research use only.

Images

References

Datasheet

Anti-Human LETM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human LETM1 Polyclonal Antibody (HF870014)

Overview

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References

Datasheet

SDS

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