Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616) (HV606013)

Name: Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616)
Brand: abinScience
SKU: HV606013
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV606013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1616

Clonality

Monoclonal

Target

PRSC1, Legumain, Asparaginyl endopeptidase, LGMN, Protease, cysteine 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99538

RRID

Anti-Human LGMN/Legumain Antibody (SAA1616) (abinScience Cat# HV606013, RRID:AB_3727377)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Legumain (LGMN) is a ~49 kDa protein. Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules.

1. Dall, E. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10940-5. PMID: 23776206

2. Manoury, B. et al. (1998) Nature 396, 695-9. PMID: 9872320

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human LGMN/Legumain Antibody (SAA1616)

References

Datasheet

Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616) (HV606013)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us