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Anti-Human LGR6 Recombinant Antibody (SAA1715) (HP792013)

Anti-Human LGR6 Recombinant Antibody (SAA1715)
Anti-Human LGR6 Recombinant Antibody (SAA1715)
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Overview
Catalog No.HP792013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1715
Clonality Monoclonal
Target Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9HBX8
RRID Anti-Human LGR6 Antibody (SAA1715) (abinScience Cat# HP792013, RRID:AB_3727476)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Leucine-rich repeat-containing G-protein coupled receptor 6 (LGR6) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Note For research use only.
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  • Anti-Human LGR6 Recombinant Antibody (SAA1715)

    SDS-PAGE

    SDS-PAGE for Anti-Human LGR6 Antibody (SAA1715)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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