

| Catalog No. | HP792013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human LGR6 Recombinant Antibody (SAA1715) (HP792013) is a mouse monoclonal antibody detecting LGR6 in ELISA. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1715 | ||||
| Target | Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9HBX8 | ||||
| RRID | Anti-Human LGR6 Antibody (SAA1715) (abinScience Cat# HP792013, RRID:AB_3727476) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Leucine-rich repeat-containing G-protein coupled receptor 6 (LGR6) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human LGR6 Antibody (SAA1715)
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