Anti-Human LMTK3 Polyclonal Antibody (HV120014)

Name: Anti-Human LMTK3 Polyclonal Antibody
Brand: abinScience
SKU: HV120014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV120014

Description

Anti-Human LMTK3 Polyclonal Antibody (HV120014) is a rabbit polyclonal antibody detecting LMTK3. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LMTK3 (Gln116-Pro416).

Target

EC:2.7.11.1, KIAA1883, LMTK3, Lemur tyrosine kinase 3, Serine/threonine-protein kinase LMTK3, TYKLM3

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q96Q04

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Serine/threonine-protein kinase LMTK3 is a ~153 kDa protein. Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription. Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons.

1. Giamas, G. et al. (2011) Nature medicine 17, 715-9. PMID: 21602804

Note

For research use only

Images

References

Datasheet

Anti-Human LMTK3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human LMTK3 Polyclonal Antibody (HV120014)

Overview

Images

References

Datasheet

SDS

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