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Anti-Human LY6H Recombinant Antibody (12G7), APC (HF755137)

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Overview
Catalog No.HF755137
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone ID12G7
ConjugationAPC
Clonality Monoclonal
Target Ly-6H, Lymphocyte antigen 6H, LY6H
Endotoxin level Please contact with the lab for this information.
Associated products Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Accession O94772
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Lymphocyte antigen 6H (LY6H) is a ~14 kDa protein. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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