Anti-Human LYVE1 Polyclonal Antibody (HV236014)

Name: Anti-Human LYVE1 Polyclonal Antibody
Brand: abinScience
SKU: HV236014
Price: 96 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HV236014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LYVE1 (Arg26-Ser131).

Target

Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1

Purification

Purified by antigen affinity column.

Accession

Q9Y5Y7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) is a ~35 kDa protein. Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium.

1. Banerji, S. et al. (1999) The Journal of cell biology 144, 789-801. PMID: 10037799

2. Lawrance, W. et al. (2016) The Journal of biological chemistry 291, 8014-30. PMID: 26823460

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-LYVE1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat brain lysate

References

Datasheet

Anti-Human LYVE1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human LYVE1 Polyclonal Antibody (HV236014)

Overview

Images

References

Datasheet

SDS

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