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Anti-Human MAGEC2 Polyclonal Antibody (HP272014)

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Overview
Catalog No.HP272014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human MAGEC2 (Asp132-Ser328).
Target MAGEC2, MAGEE1, HCA587, Cancer/testis antigen 10, MAGE-C2 antigen, MAGE-E1 antigen, CT10, Melanoma-associated antigen C2, Hepatocellular carcinoma-associated antigen 587
Purification Purified by antigen affinity column.
Accession Q9UBF1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Melanoma-associated antigen C2 (MAGEC2) is a ~41 kDa protein. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Anti-Human MAGEC2 Polyclonal Antibody

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