Anti-Human MAP1LC3C Polyclonal Antibody (HP758014)

Name: Anti-Human MAP1LC3C Polyclonal Antibody
Brand: abinScience
SKU: HP758014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HP758014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MAP1LC3C (Arg11-Leu147).

Target

Microtubule-associated proteins 1A/1B light chain 3C, MAP1A/MAP1B LC3 C, Autophagy-related ubiquitin-like modifier LC3 C, MAP1A/MAP1B light chain 3 C, Microtubule-associated protein 1 light chain 3 gamma, MAP1 light chain 3-like protein 3, MAP1LC3C, Autophagy-related protein LC3 C

Purification

Purified by antigen affinity column.

Accession

Q9BXW4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) is a ~16 kDa protein. Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins.

1. von Muhlinen, N. et al. (2012) Molecular cell 48, 329-42. PMID: 23022382

2. Liu, X. et al. (2017) The Journal of cell biology 216, 1301-1320. PMID: 28404643

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human MAP1LC3C polyclonal antibody at 1ug/mL on recombinant Human MAP1LC3C (Catalog No. HP758012).

References

Datasheet

Anti-Human MAP1LC3C Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MAP1LC3C Polyclonal Antibody (HP758014)

Overview

Images

References

Datasheet

SDS

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