

| Catalog No. | HT165014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MAP3K13 Polyclonal Antibody (HT165014) is a rabbit polyclonal antibody detecting MAP3K13 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human MAP3K13 (Trp161-Pro418). | ||||||||
| Target | Mitogen-activated protein kinase kinase kinase 13, 2.7.11.25, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13, LZK | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O43283 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Mitogen-activated protein kinase kinase kinase 13 (MAP3K13) is a ~108 kDa protein. Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. | ||||||||
| Note | For research use only. |
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