Anti-Human MAP3K14 Recombinant Antibody (SAA1891) (HA232013)

Name: Anti-Human MAP3K14 Recombinant Antibody (SAA1891)
Brand: abinScience
SKU: HA232013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA232013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1891

Clonality

Monoclonal

Target

NF-kappa-beta-inducing kinase, NIK, HsNIK, Mitogen-activated protein kinase kinase kinase 14, MAP3K14, Serine/threonine-protein kinase NIK

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99558

RRID

Anti-Human MAP3K14 Antibody (SAA1891) (abinScience Cat# HA232013, RRID:AB_3727655)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Mitogen-activated protein kinase kinase kinase 14 (MAP3K14) is a ~104 kDa protein. Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Phosphorylates CHUK/IKKA, thereby promoting proteolytic processing of NFKB2/P100, which leads to NF-kappa-B activation via the non-canonical pathway. Has an essential role in the non-canonical NF-kappa-B signaling that regulates genes encoding molecules involved in B-cell survival, lymphoid organogenesis, and immune response. Could act in a receptor-selective manner.

1. Willmann, KL. et al. (2014) Nature communications 5, 5360. PMID: 25406581

2. Schlechter, N. et al. (2017) Frontiers in immunology 8, 1624. PMID: 29230214

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MAP3K14 Antibody (SAA1891)

References

Datasheet

Anti-Human MAP3K14 Recombinant Antibody (SAA1891).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MAP3K14 Recombinant Antibody (SAA1891) (HA232013)

Overview

Images

References

Datasheet

SDS

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