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Anti-Human MB Monoclonal Antibody (1A601) (HF785065)

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Anti-Human MB Monoclonal Antibody (1A601)

Anti-Human MB Monoclonal Antibody (1A601)

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Overview

Catalog No.	HF785065
Description	Anti-Human MB Monoclonal Antibody (1A601) [1A601] (HF785065) is a mouse monoclonal antibody detecting Human MB in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A601
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human MB (Met1-Gly154).
Target	Myoglobin, Nitrite reductase MB, EC:1.7.-.-, Pseudoperoxidase MB, EC:1.11.1.-, MB
Purification	Protein A/G purified from cell culture supernatant.
Accession	P02144
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Myoglobin (MB) is a ~17 kDa protein. Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. 1. Olivé, M. et al. (2019) Nature communications 10, 1396. PMID: 30918256 2. Hofbauer, S. et al. (2022) The FEBS journal 289, 1105-1117. PMID: 34679218 3. Quesnelle, K. et al. (2020) Nitric oxide : biology and chemistry 104-105, 36-43. PMID: 32891753
Note	For research use only.

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SDS-PAGE for Anti-Human MB Monoclonal Antibody (1A601)

References

Datasheet

Anti-Human MB Monoclonal Antibody (1A601).pdf

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Anti-Human MB Monoclonal Antibody (1A601)