

| Catalog No. | HC355014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MEF2C Polyclonal Antibody (HC355014) is a rabbit polyclonal antibody detecting MEF2C in ELISA, IHC, WB. Suitable for Bovine, Chicken, Human, Mouse, and Pongo abelii.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MEF2C (Arg10-Gly95). | ||||||||
| Target | MEF2C, Myocyte-specific enhancer factor 2C, Myocyte enhancer factor 2C | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q06413 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Myocyte-specific enhancer factor 2C (MEF2C) is a ~51 kDa protein. Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. | ||||||||
| Note | For research use only. |



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