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Anti-Human MEP1B Polyclonal Antibody (HS728014)

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Overview
Catalog No.HS728014
Description
Anti-Human MEP1B Polyclonal Antibody (HS728014) is a rabbit polyclonal antibody detecting MEP1B. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human MEP1B (Ile37-Tyr253).
Target EC:3.4.24.63, Endopeptidase-2, MEP1B, Meprin A subunit beta, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q16820
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Meprin A subunit beta (MEP1B) is a ~79 kDa protein. Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

1. Schmidt, F. et al. (2016) Biological chemistry. PMID: 27180357
Note For research use only
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Formula
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Anti-Human MEP1B Polyclonal Antibody

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