

| Catalog No. | HV142014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MEPE Polyclonal Antibody (HV142014) is a rabbit polyclonal antibody detecting MEPE in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MEPE (Ser212-Asn445). | ||||||||
| Target | MEPE | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NQ76 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | Matrix extracellular phosphoglycoprotein, Osteoblast/osteocyte factor 45, OF45, Osteoregulin, MEPE | ||||||||
| Background | Matrix extracellular phosphoglycoprotein (MEPE) is a ~58 kDa protein. Promotes renal phosphate excretion and inhibits intestinal phosphate absorption. Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage. Promotes dental pulp stem cell proliferation and differentiation. 1. Rowe, PS. et al. (2004) Bone 34, 303-19. PMID: 14962809 2. Marks, J. et al. (2008) Journal of the American Society of Nephrology : JASN 19, 2313-20. PMID: 19005008 3. Martin, A. et al. (2008) Endocrinology 149, 1757-72. PMID: 18162525 4. Boskey, AL. et al. (2010) Calcified tissue international 86, 42-6. PMID: 19998030 5. Staines, KA. et al. (2012) Bone 51, 418-30. PMID: 22766095 6. Wei, X. et al. (2012) Journal of endodontics 38, 330-8. PMID: 22341070 | ||||||||
| Note | For research use only. |
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