

| Catalog No. | HC844014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MGST3 Polyclonal Antibody (HC844014) is a rabbit polyclonal antibody detecting MGST3. Suitable for Human and Mouse.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MGST3 (Ser30-Pro70). | ||||||||
| Target | EC:1.11.1.-, EC:2.5.1.-, EC:4.4.1.20, GST-3, Glutathione S-transferase 3, mitochondrial, Glutathione peroxidase MGST3, LTC4 synthase MGST3, MGST3 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O14880 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Glutathione S-transferase 3, mitochondrial (MGST3) is a ~16 kDa protein. Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites. Catalyzes conjugate addition of reduced glutathione to the alpha, beta-unsaturated C=C carbonyl group of eisosanoids such as leukotriene A4 and 15-deoxy-Delta12,14-prostaglandin J2 to form GSH adducts relevant to the inflammatory response. Catalyzes glutathione-dependent reduction of eicosanoid peroxides to yield the corresponding eicosanoid hydroxides. 1. Steinmetz-Späh, J. et al. (2022) Journal of lipid research 63, 100310. PMID: 36370807 2. Jakobsson, PJ. et al. (1997) The Journal of biological chemistry 272, 22934-9. PMID: 9278457 | ||||||||
| Note | For research use only |
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