Anti-Human MMP2 Recombinant Antibody (3G11) (HY431023)

Name: Anti-Human MMP2 Recombinant Antibody (3G11)
Brand: abinScience
SKU: HY431023
Price: 110 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY431023

Species reactivity

Human

Applications

ELISA, IF

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

3G11

Clonality

Monoclonal

Target

72 kDa gelatinase, Matrix metalloproteinase-2, Gelatinase A, TBE-1, MMP2, CLG4A, 72 kDa type IV collagenase, MMP-2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08253

RRID

Anti-Human MMP2 Antibody (3G11) (abinScience Cat# HY431023, RRID:AB_3727010)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

72 kDa type IV collagenase (MMP2) is a ~73 kDa protein. Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta.

Note

For research use only.

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