Anti-Human MMP24 Polyclonal Antibody (HV667024)

Name: Anti-Human MMP24 Polyclonal Antibody
Brand: abinScience
SKU: HV667024
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV667024

Description

Anti-Human MMP24 Polyclonal Antibody (HV667024) is a rabbit polyclonal antibody detecting MMP24. Suitable for Rat, Mouse, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MMP24 (Ile379-Trp566).

Target

EC:3.4.24.-, MMP-24, MMP24, MT-MMP 5, MT5-MMP, MT5MMP, MTMMP5, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, Processed matrix metalloproteinase-24

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q9Y5R2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Matrix metalloproteinase-24 (MMP24) is a ~73 kDa protein. Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A.

Note

For research use only

Images

References

Datasheet