Anti-Human/Mouse/Rat CCL2/MCP-1 Recombinant Antibody (2H5) (HY280033)

Name: Anti-Human/Mouse/Rat CCL2/MCP-1 Recombinant Antibody (2H5)
Brand: abinScience
SKU: HY280033
Price: 191 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY280033

Species reactivity

Human, Mouse, Rat

Applications

ELISA, FACS, Functional assay, Research in vivo

Host species

Armenian hamster

Isotype

IgG

Clone ID

2H5

Clonality

Monoclonal

Target

C-C motif chemokine 2, CCL2, HC11, MCAF, MCP-1, MCP1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2

Endotoxin level

<1 EU/mg

Purity

>95% as determined by SDS-PAGE.

Associated products

pH 7.4 Dilution Buffer

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13500, P10148, P14844

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

C-C motif chemokine 2 (CCL2/MCP-1) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171

2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439

3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883

4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247

5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182

6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674

7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690

Note

For research use only

Images

References

Datasheet

Anti-Human/Mouse/Rat CCL2/MCP-1 Recombinant Antibody (2H5).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human/Mouse/Rat CCL2/MCP-1 Recombinant Antibody (2H5) (HY280033)

Overview

Images

References

Datasheet

SDS

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