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Anti-Human/Mouse ZNFX1 Polyclonal Antibody (HA408014)

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Overview
Catalog No.HA408014
Description
Anti-Human/Mouse ZNFX1 Polyclonal Antibody (HA408014) is a rabbit polyclonal antibody detecting ZNFX1 in WB, IHC, ELISA. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsWB, IHC, ELISA
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human ZNFX1 (Asn1070-Asp1310).
Target ZNFX1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9P2E3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesNFX1-type zinc finger-containing protein 1, ZNFX1, KIAA1404
Background

NFX1-type zinc finger-containing protein 1 (ZNFX1) is a ~220 kDa protein. RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses. Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response. Also required for immunity against some bacteria, such as mycobacteria.

1. Vavassori, S. et al. (2021) The Journal of allergy and clinical immunology 148, 381-393. PMID: 33872655
2. Le Voyer, T. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 33876776
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human/Mouse ZNFX1 Polyclonal Antibody

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