Anti-Human MSH6 IP Recombinant Antibody (SAA0212) (HW445013)

Name: Anti-Human MSH6 IP Recombinant Antibody (SAA0212)
Brand: abinScience
SKU: HW445013
Price: 191 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW445013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA0212

Clonality

Monoclonal

Target

DNA mismatch repair protein Msh6, MutS protein homolog 6, MSH6, GTBP, hMSH6, GTMBP, G/T mismatch-binding protein, MutS-alpha 160 kDa subunit, p160

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P52701

RRID

Anti-Human MSH6 IP Antibody (SAA0212) (abinScience Cat# HW445013, RRID:AB_3729746)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

DNA mismatch repair protein Msh6 is a ~152 kDa protein. Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MSH6 IP Antibody (SAA0212)

References

Datasheet

Anti-Human MSH6 IP Recombinant Antibody (SAA0212).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MSH6 IP Recombinant Antibody (SAA0212) (HW445013)

Overview

Images

References

Datasheet

SDS

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