

| Catalog No. | HA093014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MTA3 Polyclonal Antibody (HA093014) is a rabbit polyclonal antibody detecting MTA3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human MTA3 (Met1-Lys147). | ||||||||
| Target | Metastasis-associated protein MTA3, MTA3, KIAA1266 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9BTC8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Metastasis-associated protein MTA3 is a ~67 kDa protein. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. 1. Fujita, N. et al. (2003) Cell 113, 207-19. PMID: 12705869 2. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440 3. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666 4. Fujita, N. et al. (2004) Cell 119, 75-86. PMID: 15454082 | ||||||||
| Note | For research use only. |
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