

| Catalog No. | HA709014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MTNR1A Polyclonal Antibody (HA709014) is a rabbit polyclonal antibody detecting Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor; MTNR1A in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant human MTNR1A (Gly296-Val350). | ||||||||
| Target | Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor; MTNR1A | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P48039 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Melatonin receptor type 1A (MTNR1A) is a ~39 kDa protein. High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Possibly involved in sleep induction, by melatonin activation of the potassium channel KCNMA1/BK and the dissociation of G-beta and G-gamma subunits, thereby decreasing synaptic transmission. | ||||||||
| Note | For research use only |
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