Anti-Human NAXE Polyclonal Antibody (HV343014)

Name: Anti-Human NAXE Polyclonal Antibody
Brand: abinScience
SKU: HV343014
Price: 96 USD
Availability: InStock

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Overview

Catalog No.

HV343014

Description

Anti-Human NAXE Polyclonal Antibody (HV343014) is a rabbit polyclonal antibody detecting NAXE in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, Sus scrofa, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human NAXE (Gly118-Glu282).

Target

NAXE

Purification

Purified by antigen affinity column.

Accession

Q8NCW5

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

NAD(P)H-hydrate epimerase, 5.1.99.6, Apolipoprotein A-I-binding protein, AI-BP, NAD(P)HX epimerase, YjeF N-terminal domain-containing protein 1, YjeF_N1, NAXE, AIBP, APOA1BP, YJEFN1

Background

NAD(P)H-hydrate epimerase (NAXE) is a ~31 kDa protein. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.

1. Kremer, LS. et al. (2016) American journal of human genetics 99, 894-902. PMID: 27616477

2. Fang, L. et al. (2013) Nature 498, 118-22. PMID: 23719382

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-NAXE polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse kidney lysate
Lane 2: Rat liver lysate
Lane 3: Rat kidney lysate
Lane 4: Rat heart lysate
Lane 5: Rat testis lysate

References

Datasheet

Anti-Human NAXE Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human NAXE Polyclonal Antibody (HV343014)

Overview

Images

References

Datasheet

SDS

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