Anti-Human NCOR1 Polyclonal Antibody (HD541014)

Name: Anti-Human NCOR1 Polyclonal Antibody
Brand: abinScience
SKU: HD541014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HD541014

Description

Anti-Human NCOR1 Polyclonal Antibody (HD541014) is a rabbit polyclonal antibody detecting NCOR1. Suitable for Human.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NCOR1 (Met424-Gly500&Trp628-Pro690).

Target

KIAA1047, N-CoR, N-CoR1, NCOR1, Nuclear receptor corepressor 1

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O75376

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Nuclear receptor corepressor 1 (NCOR1) is a ~270 kDa protein. Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation. Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression.

1. Cui, J. et al. (2011) Cellular and molecular life sciences : CMLS 68, 1091-103. PMID: 20812024

Note

For research use only

Images

Western blot

Lane 1: K562 cell lysate
Lane 2: NIH3T3 cell lysate
Lane 3: 293T cell lysate
Lane 4: Hela cell lysate

References

Datasheet

Anti-Human NCOR1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human NCOR1 Polyclonal Antibody (HD541014)

Overview

Images

References

Datasheet

SDS

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