

| Catalog No. | HP376014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human NDUFA13 (Met51-Thr144). | ||||||||
| Target | Gene associated with retinoic and IFN-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, CI-B16.6, Cell death regulatory protein GRIM-19, NADH-ubiquinone oxidoreductase B16.6 subunit, GRIM-19, Complex I-B16.6, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, GRIM19, NDUFA13 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9P0J0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13) is a ~16 kDa protein. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. 1. Stroud, DA. et al. (2016) Nature 538, 123-126. PMID: 27626371 2. Barnich, N. et al. (2005) The Journal of biological chemistry 280, 19021-6. PMID: 15753091 | ||||||||
| Note | For research use only. |


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