

| Catalog No. | HD087014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human NEK3 Polyclonal Antibody (HD087014) is a rabbit polyclonal antibody detecting NEK3. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human NEK3 (Met1-Thr288). | ||||||||
| Target | EC:2.7.11.1, HSPK 36, NEK3, Never in mitosis A-related kinase 3, NimA-related protein kinase 3, Serine/threonine-protein kinase Nek3 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P51956 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Serine/threonine-protein kinase Nek3 is a ~57 kDa protein. Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. | ||||||||
| Note | For research use only |
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