Anti-Human NHERF-3/PDZK1 Polyclonal Antibody (HA122014)

Name: Anti-Human NHERF-3/PDZK1 Polyclonal Antibody
Brand: abinScience
SKU: HA122014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA122014

Description

Anti-Human NHERF-3/PDZK1 Polyclonal Antibody (HA122014) is a rabbit polyclonal antibody detecting NHERF-3. Suitable for Human.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NHERF-3/PDZK1 (Met1-Ser341).

Target

CAP70, CFTR-associated protein of 70 kDa, NHERF-3, NHERF3, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, NaPi-Cap1, PDZ domain-containing protein 1, PDZD1, PDZK1, Sodium-hydrogen exchanger regulatory factor 3

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q5T2W1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3/PDZK1) is a ~57 kDa protein. A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity.

Note

For research use only

Images

References

Datasheet

Anti-Human NHERF-3/PDZK1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human NHERF-3/PDZK1 Polyclonal Antibody (HA122014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us