Anti-Human NLRP2 Polyclonal Antibody (HD439014)

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Overview

Catalog No.

HD439014

Description

Anti-Human NLRP2 Polyclonal Antibody (HD439014) is a rabbit polyclonal antibody detecting NLRP2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NLRP2 (Glu614-Glu1046).

Target

NACHT, LRR and PYD domains-containing protein 2, NALP2, NBS1, NLRP2, Nucleotide-binding site protein 1, PAN1, PYPAF2, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q9NX02

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Q9NX02

Background

NACHT, LRR and PYD domains-containing protein 2 (NLRP2) is a ~120 kDa protein. Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature pro-inflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of pro-inflammatory caspases.

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-NLRP2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: A549 cell lysate
Lane 2: K562 cell lysate

References

Datasheet

Anti-Human NLRP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human NLRP2 Polyclonal Antibody (HD439014)

Overview

Images

References

Datasheet

SDS

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