

| Catalog No. | HC154035 |
|---|---|
| Description |
Anti-Human NR5A1 Monoclonal Antibody (1A708) [1A708] (HC154035) is a mouse monoclonal antibody detecting NR5A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, IHC, WB |
| Host species | Mouse |
| Isotype | IgG |
| Clone ID | 1A708 |
| Clonality | Monoclonal |
| Immunogen | E. coli - derived recombinant human NR5A1 (Glu225-Thr461). |
| Target | Steroidogenic factor 1, SF-1, STF-1, hSF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP, NR5A1 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q13285 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Steroidogenic factor 1 (NR5A1) is a ~51 kDa protein. Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. 1. Bashamboo, A. et al. (2016) Human molecular genetics 25, 3446-3453. PMID: 27378692 |
| Note | For research use only. |

SDS-PAGE for Anti-Human NR5A1 Monoclonal Antibody (1A708)



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