

| Catalog No. | HP998014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human NSD3/WHSC1L1 (Lys267-Thr391). | ||||||||
| Target | Wolf-Hirschhorn syndrome candidate 1-like protein 1, NSD3, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, Nuclear SET domain-containing protein 3, WHSC1-like protein 1, WHSC1L1, Protein whistle, Histone-lysine N-methyltransferase NSD3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9BZ95 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Histone-lysine N-methyltransferase NSD3 (WHSC1L1) is a ~161 kDa protein. Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. | ||||||||
| Note | For research use only. |


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