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Anti-Human NSD3/WHSC1L1 Polyclonal Antibody (HP998014)

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Overview
Catalog No.HP998014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human NSD3/WHSC1L1 (Lys267-Thr391).
Target Wolf-Hirschhorn syndrome candidate 1-like protein 1, NSD3, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, Nuclear SET domain-containing protein 3, WHSC1-like protein 1, WHSC1L1, Protein whistle, Histone-lysine N-methyltransferase NSD3
Purification Purified by antigen affinity column.
Accession Q9BZ95
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Histone-lysine N-methyltransferase NSD3 (WHSC1L1) is a ~161 kDa protein. Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.

Note For research use only.
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Formula
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