Anti-Human NSUN5 Polyclonal Antibody (HP203014)

Name: Anti-Human NSUN5 Polyclonal Antibody
Brand: abinScience
SKU: HP203014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HP203014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NSUN5 (Met1-Arg429).

Target

NOL1R, NOL1-related protein, NSUN5, 28S rRNA (cytosine-C(5))-methyltransferase, WBSCR20A, NOL1/NOP2/Sun domain family member 5, WBSCR20, NSUN5A, Williams-Beuren syndrome chromosomal region 20A protein

Purification

Purified by antigen affinity column.

Accession

Q96P11

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

28S rRNA (cytosine-C(5))-methyltransferase (NSUN5) is a ~46 kDa protein. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development.

1. Sharma, S. et al. (2013) Nucleic acids research 41, 9062-76. PMID: 23913415

2. Janin, M. et al. (2019) Acta neuropathologica 138, 1053-1074. PMID: 31428936

3. Heissenberger, C. et al. (2019) Nucleic acids research 47, 11807-11825. PMID: 31722427

Note

For research use only.

Images

References

Datasheet

Anti-Human NSUN5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human NSUN5 Polyclonal Antibody (HP203014)

Overview

Images

References

Datasheet

SDS

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