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Anti-Human NTAN1/PNAd Recombinant Antibody (SAA1874) (HA244013)

Anti-Human NTAN1/PNAd Recombinant Antibody (SAA1874)
Anti-Human NTAN1/PNAd Recombinant Antibody (SAA1874)
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Overview
Catalog No.HA244013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1874
Clonality Monoclonal
Target NTAN1, PNAA, Protein N-terminal asparagine amidohydrolase, Protein NH2-terminal asparagine deamidase, Protein NTN-amidase, Protein N-terminal Asn amidase, Protein N-terminal asparagine amidase, PNAD, Protein NH2-terminal asparagine amidohydrolase
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q96AB6
RRID

Anti-Human NTAN1/PNAd Antibody (SAA1874) (abinScience Cat# HA244013, RRID:AB_3727637)
_x005F_x005F_x000D_

Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Protein N-terminal asparagine amidohydrolase (NTAN1/PNAd) is a ~34 kDa protein. N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn.

Note For research use only.
Images
  • Anti-Human NTAN1/PNAd Recombinant Antibody (SAA1874)

    SDS-PAGE

    SDS-PAGE for Anti-Human NTAN1/PNAd Antibody (SAA1874)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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