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Anti-Human OPRK1 Polyclonal Antibody (HW387014)

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Overview
Catalog No.HW387014
Description
Anti-Human OPRK1 Polyclonal Antibody (HW387014) is a rabbit polyclonal antibody detecting OPRK1. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human OPRK1 (Asp2-Ala57&Asp334-Val380).
Target K-OR-1, KOR-1, Kappa-type opioid receptor, OPRK, OPRK1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P41145
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Kappa-type opioid receptor (OPRK1) is a ~42 kDa protein. G-protein coupled opioid receptor that functions as a receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as a receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Note For research use only
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Formula
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Anti-Human OPRK1 Polyclonal Antibody

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