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Anti-Human PABPC4 Polyclonal Antibody (HC501014)

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Overview
Catalog No.HC501014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human PABPC4 (Met10-Asp225).
Target Activated-platelet protein 1, APP-1, PABP4, PABPC4, APP1, Inducible poly(A)-binding protein, PABP-4, Polyadenylate-binding protein 4, Poly(A)-binding protein 4, iPABP
Purification Purified by antigen affinity column.
Accession Q13310
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Polyadenylate-binding protein 4 (PABPC4) is a ~70 kDa protein. Binds the poly(A) tail of mRNA. Binds to SMIM26 mRNA and plays a role in its post-transcriptional regulation. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.

1. Yang, H. et al. (1995) Molecular and cellular biology 15, 6770-6. PMID: 8524242
2. Meng, K. et al. (2023) EMBO reports 24, e56282. PMID: 37009826
Note For research use only.
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Formula
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Anti-Human PABPC4 Polyclonal Antibody

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