

| Catalog No. | HA369014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PAK6 Polyclonal Antibody (HA369014) is a rabbit polyclonal antibody detecting PAK6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PAK6 (Thr386-Cys681). | ||||||||
| Target | PAK-6, PAK5, PAK-5, PAK6, p21-activated kinase 6, Serine/threonine-protein kinase PAK 6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NQU5 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Serine/threonine-protein kinase PAK 6 (PAK6) is a ~74 kDa protein. Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Also inhibits ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. | ||||||||
| Note | For research use only. |
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