Anti-Human pan-FZD Recombinant Antibody (F6) (HV162307)

Name: Anti-Human pan-FZD Recombinant Antibody (F6)
Brand: abinScience
SKU: HV162307
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV162307
Species reactivity	Human
Applications	ELISA, FCM, IF, SPR
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	F6
Clonality	Monoclonal
Target	FzE1, Frizzled-1, hFz1, Fz-1, FZD1, Frizzled-2, FzE2, Fz-2, hFz2, FZD2, Frizzled-5, FzE5, C2orf31, hFz5, FZD5, Fz-5, Frizzled-7, hFz7, FzE3, Fz-7, FZD7, hFz8, Frizzled-8, Fz-8, FZD8
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9UP38, Q14332, Q13467, O75084, Q9H461
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. 1. Gazit, A. et al. (1999) Oncogene 18, 5959-66. PMID: 10557084
Note	For research use only.

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Formula

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Overview