Anti-Human papillomavirus type 16 E7/Protein E7 Recombinant Nanobody (SAA1326) (VK556053)

Name: Anti-Human papillomavirus type 16 E7/Protein E7 Recombinant Nanobody (SAA1326)
Brand: abinScience
SKU: VK556053
Price: 191 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK556053

Description

Anti-Human papillomavirus type 16 E7/Protein E7 Nanobody (SAA1326) [SAA1326] (VK556053) is a alpaca monoclonal antibody detecting Protein E7 in ELISA.

Species reactivity

Human papillomavirus 16 (HPV16)

Applications

ELISA

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

SAA1326

Clonality

Monoclonal

Target

Protein E7, E7

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P03129

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein E7 (ProteinE7) is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.

Note

For research use only.

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