Anti-Human PCBP2 Polyclonal Antibody (HS896014)

Name: Anti-Human PCBP2 Polyclonal Antibody
Brand: abinScience
SKU: HS896014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HS896014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PCBP2 (Asn11-Ser173).

Target

Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2

Purification

Purified by antigen affinity column.

Accession

Q15366

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Poly(rC)-binding protein 2 (PCBP2) is a ~38 kDa protein. Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Also binds poly(rU). Acts as a negative regulator of antiviral signaling. Negatively regulates cellular antiviral responses mediated by MAVS signaling.

1. Walter, BL. et al. (2002) Journal of virology 76, 12008-22. PMID: 12414943

2. Leffers, H. et al. (1995) European journal of biochemistry 230, 447-53. PMID: 7607214

3. You, F. et al. (2009) Nature immunology 10, 1300-8. PMID: 19881509

4. Gu, H. et al. (2022) Nature communications 13, 1564. PMID: 35322803

Note

For research use only.

Images

References

Datasheet

Anti-Human PCBP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PCBP2 Polyclonal Antibody (HS896014)

Overview

Images

References

Datasheet

SDS

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