

| Catalog No. | HS831014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PDCD4/PD4 Polyclonal Antibody (HS831014) is a rabbit polyclonal antibody detecting PDCD4 in ELISA, IHC, WB. Suitable for Chicken, Human, Mouse, Pongo abelii, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human PDCD4/PD4 (Phe164-Tyr469). | ||||||||
| Target | PDCD4, Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, Protein 197/15a, H731, Programmed cell death protein 4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q53EL6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Programmed cell death protein 4 (PDCD4/PD4) is a ~51 kDa protein. Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. | ||||||||
| Note | For research use only. |
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