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Anti-Human PDE2A Polyclonal Antibody (HT386014)

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Overview
Catalog No.HT386014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human PDE2A (Asp241-Gln387).
Target cGMP-dependent 3', 5'-cyclic phosphodiesterase, CGS-PDE, PDE2A, cGSPDE, Cyclic GMP-stimulated phosphodiesterase
Purification Purified by antigen affinity column.
Accession O00408
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A) is a ~105 kDa protein. cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. Plays a role in cell growth and migration.

1. Iffland, A. et al. (2005) Biochemistry 44, 8312-25. PMID: 15938621
2. Salpietro, V. et al. (2018) Movement disorders : official journal of the Movement Disorder Society 33, 482-488. PMID: 29392776
3. Rosman, GJ. et al. (1997) Gene 191, 89-95. PMID: 9210593
4. Hiramoto, K. et al. (2014) Cellular signalling 26, 1807-17. PMID: 24705027
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human PDE2A Polyclonal Antibody

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