

| Catalog No. | HP441014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PHOX2B (Thr106-Gly173). | ||||||||
| Target | PMX2B, PHOX2B homeodomain protein, Paired-like homeobox 2B, Neuroblastoma Phox, Paired mesoderm homeobox protein 2B, NBPhox, PHOX2B | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q99453 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Paired mesoderm homeobox protein 2B (PHOX2B) is a ~31 kDa protein. Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. | ||||||||
| Note | For research use only. |




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