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Anti-Human PHOX2B Polyclonal Antibody (HP441014)

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Overview
Catalog No.HP441014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human PHOX2B (Thr106-Gly173).
Target PMX2B, PHOX2B homeodomain protein, Paired-like homeobox 2B, Neuroblastoma Phox, Paired mesoderm homeobox protein 2B, NBPhox, PHOX2B
Purification Purified by antigen affinity column.
Accession Q99453
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Paired mesoderm homeobox protein 2B (PHOX2B) is a ~31 kDa protein. Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Note For research use only.
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